Which of the following requires a DEA 222 order form for purchase?

The requirement for a DEA 222 order form is specific to certain controlled substances, particularly those classified under Schedule I and II. In this context, marijuana, while legal in many states for medicinal or recreational use, remains classified as a Schedule I substance under federal law, according to the Controlled Substances Act. This means that it cannot be legally purchased or distributed without following strict regulatory processes, including the usage of a DEA 222 order form.

On the other hand, cocaine, which is classified as a Schedule II substance, also requires a DEA 222 order form for its purchase. Clonazepam and modafinil, however, belong to Schedule IV and Schedule IV controlled substances, respectively, neither of which requires a DEA 222 form for procurement. Schedule IV substances typically require a prescription but can be ordered using less stringent methods than Schedule I and II drugs.

Thus, the DEA 222 order form is essential for the purchase of certain highly regulated drugs, with marijuana being a notable example due to its federal classification as a Schedule I substance.